Catalytic enantioselective C-H functionalization of alcohols by redox-triggered carbonyl addition: borrowing hydrogen, returning carbon.
Angew Chem Int Ed Engl
; 53(35): 9142-50, 2014 Aug 25.
Article
em En
| MEDLINE
| ID: mdl-25056771
ABSTRACT
The use of alcohols and unsaturated reactants for the redox-triggered generation of nucleophile-electrophile pairs represents a broad, new approach to carbonyl addition chemistry. Discrete redox manipulations that are often required for the generation of carbonyl electrophiles and premetalated carbon-centered nucleophiles are thus avoided. Based on this concept, a broad, new family of enantioselective C-C coupling reactions that are catalyzed by iridium or ruthenium complexes have been developed, which are summarized in this Minireview.
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MEDLINE
Assunto principal:
Carbono
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Álcoois
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Hidrogênio
Idioma:
En
Ano de publicação:
2014
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Article