Human cardiac fibroblast extracellular matrix remodeling: dual effects of tissue inhibitor of metalloproteinase-2.

Ngu, Janet M C; Teng, Guoqi; Meijndert, Hans Christopher; Mewhort, Holly E; Turnbull, Jeannine D; Stetler-Stevenson, William G; Fedak, Paul W M

Ngu, Janet M C; Teng, Guoqi; Meijndert, Hans Christopher; Mewhort, Holly E; Turnbull, Jeannine D; Stetler-Stevenson, William G; Fedak, Paul W M.

Afiliação

Ngu JM; Section of Cardiac Surgery, Department of Cardiac Sciences, University of Calgary, Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Teng G; Section of Cardiac Surgery, Department of Cardiac Sciences, University of Calgary, Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Meijndert HC; Section of Cardiac Surgery, Department of Cardiac Sciences, University of Calgary, Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Mewhort HE; Section of Cardiac Surgery, Department of Cardiac Sciences, University of Calgary, Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Turnbull JD; Section of Cardiac Surgery, Department of Cardiac Sciences, University of Calgary, Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada.
Stetler-Stevenson WG; Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Fedak PW; Section of Cardiac Surgery, Department of Cardiac Sciences, University of Calgary, Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada. Electronic address: paul.fedak@gmail.com.

Cardiovasc Pathol ; 23(6): 335-43, 2014.

Article em En | MEDLINE | ID: mdl-25060386

Assuntos

Fibroblastos/citologia; Fibroblastos/metabolismo; Miocárdio/citologia; Miocárdio/metabolismo; Inibidor Tecidual de Metaloproteinase-2/metabolismo; Apêndice Atrial/citologia; Apêndice Atrial/metabolismo; Remodelamento Atrial/fisiologia; Células Cultivadas; Microambiente Celular/fisiologia; Colágeno/biossíntese; Matriz Extracelular/metabolismo; Humanos; Metaloproteinases da Matriz/metabolismo; Modelos Cardiovasculares

Palavras-chave

Cardiac fibroblasts; Extracellular matrix; Human cells; Remodelling; TIMP-2

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidor Tecidual de Metaloproteinase-2 / Fibroblastos / Miocárdio Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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