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Vitamin D deficiency in Korean children: prevalence, risk factors, and the relationship with parathyroid hormone levels.
Chung, In Hyuk; Kim, Hae Jung; Chung, Sochung; Yoo, Eun-Gyong.
Afiliação
  • Chung IH; Department of Pediatrics, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
  • Kim HJ; Department of Pediatrics, CHA Bundang Medical Center, CHA University College of Medicine, Seongnam, Korea.
  • Chung S; Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
  • Yoo EG; Department of Pediatrics, CHA Bundang Medical Center, CHA University College of Medicine, Seongnam, Korea.
Ann Pediatr Endocrinol Metab ; 19(2): 86-90, 2014 Jun.
Article em En | MEDLINE | ID: mdl-25077091
ABSTRACT

PURPOSE:

This study was performed to investigate the relationship between serum vitamin D and parathyroid hormone (PTH) levels as well as to describe the prevalence and the risk factors of vitamin D deficiency (VDD) in Korean children.

METHODS:

Participants were 1,212 children aged 4 to 15 years, who visited Bundang CHA Medical Center (located at 37°N) between March 2012 and February 2013. Overweight was defined as body mass index≥85th percentile. Participants were divided into 4 age groups and 2 seasonal groups. VDD was defined by serum 25-hydroxyvitamin D (25OHD) <20 ng/mL.

RESULTS:

The level of 25OHD was significantly lower in overweight group than in normal weight group (17.1±5.1 ng/mL vs. 19.1±6.1 ng/mL, P<0.001). Winter-spring season (odds ratio [OR], 4.46; 95% confidence interval [CI], 3.45-5.77), older age group (OR, 1.60; 95% CI, 1.36-1.88), and overweight (OR, 2.21; 95% CI, 1.62-3.01) were independently related with VDD. The PTH levels were significantly higher in VDD group compared to vitamin D insufficiency and sufficiency group (P<0.001). In normal weight children, 25OHD (ß=-0.007, P<0.001) and ionized calcium (ß=-0.594, P=0.007) were independently related with PTH, however, these associations were not significant in overweight children.

CONCLUSION:

VDD is very common in Korean children and its prevalence increases in winter-spring season, in overweight children and in older age groups. Further investigation on the vitamin D and PTH metabolism according to adiposity is required.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2014 Tipo de documento: Article