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Dimerization of the kinase ARAF promotes MAPK pathway activation and cell migration.
Mooz, Juliane; Oberoi-Khanuja, Tripat Kaur; Harms, Gregory S; Wang, Weiru; Jaiswal, Bijay S; Seshagiri, Somasekar; Tikkanen, Ritva; Rajalingam, Krishnaraj.
Afiliação
  • Mooz J; Cell death signalling group, Institute of Biochemistry II, Goethe University Medical School, Frankfurt 60590, Germany. Institute for Immunology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstraße 1, Building 708, Mainz 55131, Germany.
  • Oberoi-Khanuja TK; Cell death signalling group, Institute of Biochemistry II, Goethe University Medical School, Frankfurt 60590, Germany.
  • Harms GS; Stark Learning Center, Department of Biology and Health Sciences, Wilkes University, Wilkes-Barre, Pennsylvania, PA 18766, USA.
  • Wang W; Department of Protein Engineering, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA.
  • Jaiswal BS; Department of Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Seshagiri S; Department of Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Tikkanen R; Institute of Biochemistry, Medical Faculty, University of Giessen, Giessen 35392, Germany.
  • Rajalingam K; Cell death signalling group, Institute of Biochemistry II, Goethe University Medical School, Frankfurt 60590, Germany. Institute for Immunology, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstraße 1, Building 708, Mainz 55131, Germany. krishna@biochem2.de.
Sci Signal ; 7(337): ra73, 2014 Aug 05.
Article em En | MEDLINE | ID: mdl-25097033
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Moleculares / Movimento Celular / Sistema de Sinalização das MAP Quinases / Proteínas Proto-Oncogênicas A-raf Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Moleculares / Movimento Celular / Sistema de Sinalização das MAP Quinases / Proteínas Proto-Oncogênicas A-raf Idioma: En Ano de publicação: 2014 Tipo de documento: Article