Comparative analysis of LTR and structural genes in an equine infectious anemia virus strain isolated from a feral horse in Japan.
Arch Virol
; 159(12): 3413-20, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-25149072
ABSTRACT
Although equine infectious anemia virus (EIAV) poses a major threat to the equine industry worldwide, the molecular epidemiology of this virus is poorly understood. Recently, an EIAV strain (EIAVMiyazaki2011-A) representing a new monophyletic group was discovered in feral horses in southern Japan. In the present study, the EIAVMiyazaki2011-A proviral genome is compared with evolutionarily divergent EIAV isolates to investigate conservation of functional elements or motifs within the long terminal repeats (LTRs) and structural genes. This analysis represents a significant step forward in increasing understanding of the molecular conservation and variation between geographically distinct strains of this equine lentivirus.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Variação Genética
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Anemia Infecciosa Equina
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Vírus da Anemia Infecciosa Equina
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Sequências Repetidas Terminais
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Cavalos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article