Impact of advanced age on the short- and long-term outcomes in patients undergoing hepatectomy for hepatocellular carcinoma: a single-center analysis over a 20-year period.
Am J Surg
; 209(4): 733-41, 2015 Apr.
Article
em En
| MEDLINE
| ID: mdl-25173600
ABSTRACT
BACKGROUND:
The purpose of this study was to analyze the influence of age on both the risk of hepatectomy and the prognosis in patients with hepatocellular carcinoma (HCC).METHODS:
Patients undergoing an initial hepatectomy for HCC were classified into 2 age groups 75 years or over (n = 113) and less than 75 years (n = 499).RESULTS:
A zero 90-day mortality was achieved in the elderly. Although the recurrence rate and recurrence sites were almost similar between the 2 groups, the 5-year survival rate in the elderly patients was significantly lower than that in the younger patients (46.0% vs 57.6%; P = .018), possibly because of the higher incidence of deaths from other causes (26.8% vs 10.4%; P = .011) in the elderly.CONCLUSION:
Selected elderly HCC patients can undergo a hepatectomy safely and can benefit from long-term HCC control comparable with that of their younger counterparts.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Carcinoma Hepatocelular
/
Hepatectomia
/
Neoplasias Hepáticas
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article