CITED2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia.

Korthuis, P M; Berger, G; Bakker, B; Rozenveld-Geugien, M; Jaques, J; de Haan, G; Schuringa, J J; Vellenga, E; Schepers, H

Korthuis, P M; Berger, G; Bakker, B; Rozenveld-Geugien, M; Jaques, J; de Haan, G; Schuringa, J J; Vellenga, E; Schepers, H.

Afiliação

Korthuis PM; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Berger G; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Bakker B; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Rozenveld-Geugien M; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Jaques J; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
de Haan G; Department of Stem Cell Biology, European Research Institute for the Biology of Aging (ERIBA), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Schuringa JJ; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Vellenga E; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Schepers H; Department of Experimental Hematology, Cancer Research Center Groningen, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Leukemia ; 29(3): 625-35, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25184385

Assuntos

Regulação Leucêmica da Expressão Gênica; Células-Tronco Hematopoéticas/metabolismo; Leucemia Mieloide Aguda/genética; Proteínas Proto-Oncogênicas/genética; Proteínas Repressoras/genética; Transativadores/genética; Animais; Antígenos CD34/genética; Antígenos CD34/metabolismo; Proliferação de Células; Inibidor de Quinase Dependente de Ciclina p21/genética; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; DNA (Citosina-5-)-Metiltransferases/genética; DNA (Citosina-5-)-Metiltransferases/metabolismo; DNA Metiltransferase 3A; Feminino; Sobrevivência de Enxerto; Transplante de Células-Tronco Hematopoéticas; Células-Tronco Hematopoéticas/patologia; Humanos; Leucemia Mieloide Aguda/metabolismo; Leucemia Mieloide Aguda/patologia; Camundongos; Camundongos Endogâmicos NOD; Mutação; Proteínas Proto-Oncogênicas/metabolismo; Proteínas Repressoras/metabolismo; Transdução de Sinais; Transativadores/metabolismo; Transplante Heterólogo; DNA Metiltransferase 3B

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Células-Tronco Hematopoéticas / Leucemia Mieloide Aguda / Regulação Leucêmica da Expressão Gênica / Transativadores / Proteínas Proto-Oncogênicas Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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