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Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aß42) aggregates leads to sub-stoichiometric inhibition of amyloid formation.
Månsson, Cecilia; Arosio, Paolo; Hussein, Rasha; Kampinga, Harm H; Hashem, Reem M; Boelens, Wilbert C; Dobson, Christopher M; Knowles, Tuomas P J; Linse, Sara; Emanuelsson, Cecilia.
Afiliação
  • Månsson C; From the Department of Biochemistry & Structural Biology, Center for Molecular Protein Science, Lund University, PO box 124, 221 00 Lund, Sweden.
  • Arosio P; Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW, Cambridge, United Kingdom.
  • Hussein R; Department of Cell Biology, UMCG and RuG, Groningen, The Netherlands, Department of Biochemistry, Faculty of Pharmacy, Beni-Suef University, Salah Salem Street, 62511 Beni-Suef, Egypt, and.
  • Kampinga HH; Department of Cell Biology, UMCG and RuG, Groningen, The Netherlands.
  • Hashem RM; Department of Biochemistry, Faculty of Pharmacy, Beni-Suef University, Salah Salem Street, 62511 Beni-Suef, Egypt, and.
  • Boelens WC; Department of Biomolecular Chemistry, Radboud University Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
  • Dobson CM; Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW, Cambridge, United Kingdom.
  • Knowles TP; Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW, Cambridge, United Kingdom.
  • Linse S; From the Department of Biochemistry & Structural Biology, Center for Molecular Protein Science, Lund University, PO box 124, 221 00 Lund, Sweden.
  • Emanuelsson C; From the Department of Biochemistry & Structural Biology, Center for Molecular Protein Science, Lund University, PO box 124, 221 00 Lund, Sweden, cecilia.emanuelsson@biochemistry.lu.se.
J Biol Chem ; 289(45): 31066-76, 2014 Nov 07.
Article em En | MEDLINE | ID: mdl-25217638

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Chaperonas Moleculares / Proteínas de Choque Térmico HSP40 / Amiloide / Proteínas do Tecido Nervoso Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Peptídeos beta-Amiloides / Chaperonas Moleculares / Proteínas de Choque Térmico HSP40 / Amiloide / Proteínas do Tecido Nervoso Idioma: En Ano de publicação: 2014 Tipo de documento: Article