First use of investigational antiviral drug pocapavir (v-073) for treating neonatal enteroviral sepsis.
Pediatr Infect Dis J
; 34(1): 52-4, 2015 Jan.
Article
em En
| MEDLINE
| ID: mdl-25229269
ABSTRACT
Neonatal enteroviral sepsis is a potentially fatal condition. Perinatally acquired infection and severe coagulopathy can be associated with a poor clinical outcome, and antiviral therapy is currently unavailable. Pocapavir (V-073) is an investigational drug candidate being developed for poliovirus indications, but also has variable antiviral activity against nonpolio enteroviruses. We describe the first use of pocapavir in treating a case of severe neonatal enteroviral sepsis due to Coxsackievirus B3.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Enterovirus Humano B
/
Sepse
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Infecções por Enterovirus
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article