The burden of selected congenital anomalies amenable to surgery in low and middle-income regions: cleft lip and palate, congenital heart anomalies and neural tube defects.
Arch Dis Child
; 100(3): 233-8, 2015 Mar.
Article
em En
| MEDLINE
| ID: mdl-25260520
ABSTRACT
OBJECTIVE:
To quantify the burden of selected congenital anomalies in low and middle-income countries (LMICs) that could be reduced should surgical programmes cover the entire population with access to quality care.DESIGN:
Burden of disease and epidemiological modelling.SETTING:
LMICs from all global regions. POPULATION All prevalent cases of selected congenital anomalies at birth in 2010. MAIN OUTCOMEMEASURES:
Disability-adjusted life years (DALYs). INTERVENTIONS ANDMETHODS:
Surgical programmes for three congenital conditions were analysed clefts (lip and palate); congenital heart anomalies; and neural tube defects. Data from the Global Burden of Disease 2010 Study were used to estimate the combination of fatal burden that could be addressed by surgical care and the additional long-term non-fatal burden associated with increased survival.RESULTS:
Of the estimated 21.6 million DALYs caused by these three conditions in LMICs, 12.4 million DALYs (57%) are potentially addressable by surgical care among the population born with such conditions. Neural tube defects have the largest potential with 76% of burden amenable by surgery, followed by clefts (59%) and congenital heart anomalies (49%). Sub-Saharan Africa and South Asia have the greatest proportion of surgically addressable burden for clefts (68%), North Africa and Middle East for congenital heart anomalies (73%), and South Asia for neural tube defects (81%).CONCLUSIONS:
There is an important and neglected role surgical programmes can play in reducing the burden of congenital anomalies in LMICs.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Fenda Labial
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Fissura Palatina
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Pessoas com Deficiência
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Cardiopatias Congênitas
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Defeitos do Tubo Neural
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article