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mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues.
Eichhorn, Stephen W; Guo, Huili; McGeary, Sean E; Rodriguez-Mias, Ricard A; Shin, Chanseok; Baek, Daehyun; Hsu, Shu-Hao; Ghoshal, Kalpana; Villén, Judit; Bartel, David P.
Afiliação
  • Eichhorn SW; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Guo H; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Institute of Molecular
  • McGeary SE; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Rodriguez-Mias RA; Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA.
  • Shin C; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Agricultural Biotechnology, Plant Genomics and Breeding Institute, Seoul National University, Seo
  • Baek D; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; Center for RNA Research, Institute for Basic Science, Seoul 151-747, Republic of Korea; School of Biological Sc
  • Hsu SH; Department of Pathology, Ohio State University, Columbus, OH 43210, USA.
  • Ghoshal K; Department of Pathology, Ohio State University, Columbus, OH 43210, USA.
  • Villén J; Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA.
  • Bartel DP; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. Electronic address: dba
Mol Cell ; 56(1): 104-15, 2014 Oct 02.
Article em En | MEDLINE | ID: mdl-25263593

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Regulação da Expressão Gênica / Estabilidade de RNA / MicroRNAs / Modelos Genéticos Idioma: En Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Regulação da Expressão Gênica / Estabilidade de RNA / MicroRNAs / Modelos Genéticos Idioma: En Ano de publicação: 2014 Tipo de documento: Article