Hypocholesterolemic effects of Lactobacillus reuteri LR6 in rats fed on high-cholesterol diet.
Int J Food Sci Nutr
; 66(1): 71-5, 2015 Feb.
Article
em En
| MEDLINE
| ID: mdl-25265203
ABSTRACT
The bacterium Lactobacillus reuteri LR6, an isolate from breast-fed human infant feces, was tested positive for bile tolerance and bile salt hydrolase activity. It was also evaluated as a potential probiotic with cholesterol-lowering effect in vivo. In this study, 32 male Albino rats were divided into four groups consisting of eight mice per group. For 60 d, group I was fed with normal synthetic diet, group II was fed with cholesterol-enriched diet only, group III was fed with cholesterol-enriched diet supplemented with skimmed milk, and group IV was fed with cholesterol-enriched diet supplemented with L. reuteri LR6-fermented skimmed milk (10(8) cfu/mL). Blood samples were taken to study lipid profile on 0th, 15th, 30th and 60th day. Compared with the control group, the values for total cholesterol (TC), triglyceride (TG), and LDL were reduced significantly in group fed with L. reuteri LR6 but for HDL this difference was not significant. The results indicated that L. reuteri LR6 might be effective as a probiotic with cholesterol-lowering activities.
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Base de dados:
MEDLINE
Assunto principal:
Colesterol na Dieta
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Limosilactobacillus reuteri
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Dieta Hiperlipídica
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Hipercolesterolemia
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Anticolesterolemiantes
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article