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Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure.
Rawat, Dhawjbahadur K; Alzoubi, Abdallah; Gupte, Rakhee; Chettimada, Sukrutha; Watanabe, Makino; Kahn, Andrea G; Okada, Takao; McMurtry, Ivan F; Gupte, Sachin A.
Afiliação
  • Rawat DK; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • Alzoubi A; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • Gupte R; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • Chettimada S; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • Watanabe M; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • Kahn AG; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • Okada T; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • McMurtry IF; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
  • Gupte SA; From the Departments of Biochemistry and Molecular Biology (D.K.R., R.G., S.C., S.A.G.), Pharmacology (A.A., I.F.M.), Lung Biology (A.A., I.F.M., S.A.G.), Internal Medicine (I.F.M.), and Pathology (A.G.K.), University of South Alabama, College of Medicine, Mobile; and Department of Physiology, Junte
Hypertension ; 64(6): 1266-74, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25267798
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Espécies Reativas de Oxigênio / Hipertrofia Ventricular Direita / Estresse Oxidativo / Insuficiência Cardíaca Diastólica / Hipertensão Pulmonar / Miocárdio Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autofagia / Espécies Reativas de Oxigênio / Hipertrofia Ventricular Direita / Estresse Oxidativo / Insuficiência Cardíaca Diastólica / Hipertensão Pulmonar / Miocárdio Idioma: En Ano de publicação: 2014 Tipo de documento: Article