Missing pieces of an ancient puzzle: evolution of the eukaryotic membrane-trafficking system.
Cold Spring Harb Perspect Biol
; 6(10): a016048, 2014 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-25274701
ABSTRACT
The membrane-trafficking system underpins cellular trafficking of material in eukaryotes and its evolution would have been a watershed in eukaryogenesis. Evolutionary cell biological studies have been unraveling the history of proteins responsible for vesicle transport and organelle identity revealing both highly conserved components and lineage-specific innovations. Recently, endomembrane components with a broad, but patchy, distribution have been observed as well, pieces that are missing from our cell biological and evolutionary models of membrane trafficking. These data together allow for new insights into the history and forces that shape the evolution of this critical cell biological system.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Transporte Biológico
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Membrana Celular
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Células Eucarióticas
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Modelos Biológicos
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article