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Highly lipophilic 3-epi-betulinic acid derivatives as potent and selective TGR5 agonists with improved cellular efficacy.
Wang, Xiao-yin; Zhang, Shu-yong; Li, Jing; Liu, Hua-nan; Xie, Xin; Nan, Fa-jun.
Afiliação
  • Wang XY; State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhang SY; State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Li J; State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Liu HN; State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Xie X; State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Nan FJ; State Key Laboratory of Drug Research, CAS Key Laboratory of Receptor Research, the National Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Acta Pharmacol Sin ; 35(11): 1463-72, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25283506
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triterpenos / Receptores Acoplados a Proteínas G Idioma: En Ano de publicação: 2014 Tipo de documento: Article