Synthesis, characterization, cytotoxicity of mixed ligand complexes of palladium(II) with dipyrido[3,2-d:2',3'-f]quinoxaline/dipyrido[3,2-a:2',3'-c](6,7,8,9-tetrahydro)phenazine and 4-toluensulfonyl-L-amino acid dianion.

Ma, Lili; Ge, Kun; Zhang, Ran; Fu, Wentao; Li, Shenghui; Wang, Shuxiang; Zhou, Guoqiang; Qin, Xinying; Zhang, Jinchao

Ma, Lili; Ge, Kun; Zhang, Ran; Fu, Wentao; Li, Shenghui; Wang, Shuxiang; Zhou, Guoqiang; Qin, Xinying; Zhang, Jinchao.

Afiliação

Ma L; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China.
Ge K; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China.
Zhang R; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China.
Fu W; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China.
Li S; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China.
Wang S; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China. Electronic address: wsx@h
Zhou G; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China.
Qin X; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China.
Zhang J; College of Chemistry & Environmental Science, Chemical Biology Key Laboratory of Hebei Province, Hebei University, Baoding 071002, China; Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Hebei University, Baoding 071002, China. Electronic address: jczha

Eur J Med Chem ; 87: 624-30, 2014 Nov 24.

Article em En | MEDLINE | ID: mdl-25299684

Assuntos

Aminoácidos/química; Ensaios de Seleção de Medicamentos Antitumorais; Paládio/química; Fenazinas/síntese química; Fenazinas/farmacologia; Quinoxalinas/síntese química; Quinoxalinas/farmacologia; Tolueno/química; Linhagem Celular Tumoral; Humanos; Espectroscopia de Ressonância Magnética; Modelos Moleculares; Fenazinas/química; Quinoxalinas/química; Espectrometria de Massas por Ionização por Electrospray

Palavras-chave

4-Toluenesulfonyl-L-amino acids; Cytotoxicity; Dpq/Dpqc; Palladium(II); Synthesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paládio / Fenazinas / Quinoxalinas / Tolueno / Ensaios de Seleção de Medicamentos Antitumorais / Aminoácidos Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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