Macroautophagy and the oncogene-induced senescence.
Front Endocrinol (Lausanne)
; 5: 157, 2014.
Article
em En
| MEDLINE
| ID: mdl-25324830
ABSTRACT
The oncogene-induced senescence is emerging as a potent tumor suppressor mechanism and as a possible therapeutic target. Macroautophagy is intimately linked to the senescence condition setup, although its role has not been elucidated yet. Here, we discuss up-to-date concepts of senescence-related macroautophagy and evaluate the current trend of this growing research field, which has relevance in future perspectives toward therapeutic options against cancer.
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MEDLINE
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En
Ano de publicação:
2014
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Article