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Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants.
Shenoi, Rajesh A; Kalathottukaren, Manu Thomas; Travers, Richard J; Lai, Benjamin F L; Creagh, A Louise; Lange, Dirk; Yu, Kai; Weinhart, Marie; Chew, Ben H; Du, Caigan; Brooks, Donald E; Carter, Cedric J; Morrissey, James H; Haynes, Charles A; Kizhakkedathu, Jayachandran N.
Afiliação
  • Shenoi RA; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Kalathottukaren MT; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Travers RJ; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Lai BF; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Creagh AL; Michael Smith Laboratories, Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.
  • Lange D; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia V5Z 1M9, Canada.
  • Yu K; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Weinhart M; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Chew BH; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia V5Z 1M9, Canada.
  • Du C; Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia V5Z 1M9, Canada.
  • Brooks DE; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada. Department of Chemistry, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Carter CJ; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
  • Morrissey JH; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  • Haynes CA; Michael Smith Laboratories, Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada.
  • Kizhakkedathu JN; Centre for Blood Research and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada. Department of Chemistry, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada. jay@pathology.ubc.ca.
Sci Transl Med ; 6(260): 260ra150, 2014 Oct 29.
Article em En | MEDLINE | ID: mdl-25355700
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Heparina / Anticoagulantes Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Heparina / Anticoagulantes Idioma: En Ano de publicação: 2014 Tipo de documento: Article