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Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines.
Driscoll, Denise L; Chakravarty, Arijit; Bowman, Doug; Shinde, Vaishali; Lasky, Kerri; Shi, Judy; Vos, Tricia; Stringer, Bradley; Amidon, Ben; D'Amore, Natalie; Hyer, Marc L.
Afiliação
  • Driscoll DL; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Chakravarty A; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Bowman D; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Shinde V; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Lasky K; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Shi J; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Vos T; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Stringer B; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Amidon B; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • D'Amore N; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
  • Hyer ML; Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, United States of America.
PLoS One ; 9(11): e111060, 2014.
Article em En | MEDLINE | ID: mdl-25365521
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Proteínas Proto-Oncogênicas / Senescência Celular / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / Inibidores de Proteínas Quinases / Mitose Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / Proteínas Proto-Oncogênicas / Senescência Celular / Proteínas Serina-Treonina Quinases / Proteínas de Ciclo Celular / Inibidores de Proteínas Quinases / Mitose Idioma: En Ano de publicação: 2014 Tipo de documento: Article