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A chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesis.
Wu, Wesley; Herrera, Zachary; Ebert, Danny; Baska, Katie; Cho, Seok H; DeRisi, Joseph L; Yeh, Ellen.
Afiliação
  • Wu W; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, USA.
  • Herrera Z; Department of Biochemistry, Stanford Medical School, Stanford, California, USA.
  • Ebert D; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, USA.
  • Baska K; Department of Biochemistry, Stanford Medical School, Stanford, California, USA.
  • Cho SH; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, USA.
  • DeRisi JL; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California, USA Howard Hughes Medical Institute, Chevy Chase, Maryland, USA joe@derisilab.ucsf.edu ellenyeh@stanford.edu.
  • Yeh E; Department of Biochemistry, Stanford Medical School, Stanford, California, USA Department of Pathology, Stanford Medical School, Stanford, California, USA Department of Microbiology and Immunology, Stanford Medical School, Stanford, California, USA joe@derisilab.ucsf.edu ellenyeh@stanford.edu.
Antimicrob Agents Chemother ; 59(1): 356-64, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25367906
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Carbolinas / Eritritol / Apicoplastos / Antimaláricos Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Carbolinas / Eritritol / Apicoplastos / Antimaláricos Idioma: En Ano de publicação: 2015 Tipo de documento: Article