Extracellular matrix assembly: a multiscale deconstruction.
Nat Rev Mol Cell Biol
; 15(12): 771-85, 2014 Dec.
Article
em En
| MEDLINE
| ID: mdl-25370693
ABSTRACT
The biochemical and biophysical properties of the extracellular matrix (ECM) dictate tissue-specific cell behaviour. The molecules that are associated with the ECM of each tissue, including collagens, proteoglycans, laminins and fibronectin, and the manner in which they are assembled determine the structure and the organization of the resultant ECM. The product is a specific ECM signature that is comprised of unique compositional and topographical features that both reflect and facilitate the functional requirements of the tissue.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Matriz Extracelular
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article