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A novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1.
Tsai, Becky Pinjou; Jimenez, Judith; Lim, Sharon; Fitzgerald, Kerry D; Zhang, Min; Chuah, Charles T H; Axelrod, Haley; Wilson, Luke; Ong, S Tiong; Semler, Bert L; Waterman, Marian L.
Afiliação
  • Tsai BP; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.
  • Jimenez J; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.
  • Lim S; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Graduate Medical School, Singapore Department of Haematology, Singapore General Hospital, Singapore.
  • Fitzgerald KD; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.
  • Zhang M; Division of Hematology/Oncology, Department of Medicine, School of Medicine, University of California, Irvine, CA, USA.
  • Chuah CT; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Graduate Medical School, Singapore Department of Haematology, Singapore General Hospital, Singapore.
  • Axelrod H; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.
  • Wilson L; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.
  • Ong ST; Cancer and Stem Cell Biology Signature Research Program, Duke-NUS Graduate Medical School, Singapore Department of Haematology, Singapore General Hospital, Singapore Department of Medical Oncology, National Cancer Centre, Singapore Department of Medicine, Duke University Medical Center, Durham, NC,
  • Semler BL; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.
  • Waterman ML; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA marian.waterman@uci.edu.
Open Biol ; 4(11): 140180, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25392452
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas de Fusão bcr-abl / Fator de Iniciação 4A em Eucariotos / Fator 1 de Ligação ao Facilitador Linfoide / Serina-Treonina Quinases TOR Idioma: En Ano de publicação: 2014 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Leucemia Mielogênica Crônica BCR-ABL Positiva / Proteínas de Fusão bcr-abl / Fator de Iniciação 4A em Eucariotos / Fator 1 de Ligação ao Facilitador Linfoide / Serina-Treonina Quinases TOR Idioma: En Ano de publicação: 2014 Tipo de documento: Article