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First-in-human dose study of the novel transforming growth factor-ß receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma.
Rodon, Jordi; Carducci, Michael A; Sepulveda-Sánchez, Juan M; Azaro, Analia; Calvo, Emiliano; Seoane, Joan; Braña, Irene; Sicart, Elisabet; Gueorguieva, Ivelina; Cleverly, Ann L; Pillay, N Sokalingum; Desaiah, Durisala; Estrem, Shawn T; Paz-Ares, Luis; Holdhoff, Matthias; Blakeley, Jaishri; Lahn, Michael M; Baselga, Jose.
Afiliação
  • Rodon J; Medical Oncology, Vall d'Hebron University Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain. jrodon@vhio.net jrodon@vhebron.net.
  • Carducci MA; Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland.
  • Sepulveda-Sánchez JM; Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Azaro A; Medical Oncology, Vall d'Hebron University Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain.
  • Calvo E; Medical Oncology, Vall d'Hebron University Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain.
  • Seoane J; Medical Oncology, Vall d'Hebron University Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain.
  • Braña I; Medical Oncology, Vall d'Hebron University Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain.
  • Sicart E; Medical Oncology, Vall d'Hebron University Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain.
  • Gueorguieva I; Eli Lilly and Company, Erl Wood, United Kingdom.
  • Cleverly AL; Eli Lilly and Company, Erl Wood, United Kingdom.
  • Pillay NS; Eli Lilly and Company, Indianapolis, Indiana.
  • Desaiah D; Eli Lilly and Company, Indianapolis, Indiana.
  • Estrem ST; Eli Lilly and Company, Indianapolis, Indiana.
  • Paz-Ares L; Hospital Virgen del Rocío, Sevilla, Spain.
  • Holdhoff M; Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland.
  • Blakeley J; Department of Neurology/Neurosurgery/and Oncology, Johns Hopkins University, Baltimore, Maryland.
  • Lahn MM; Eli Lilly and Company, Indianapolis, Indiana.
  • Baselga J; Medical Oncology, Vall d'Hebron University Hospital and Universitat Autonoma de Barcelona, Barcelona, Spain.
Clin Cancer Res ; 21(3): 553-60, 2015 Feb 01.
Article em En | MEDLINE | ID: mdl-25424852
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Quinolinas / Inibidores de Proteínas Quinases / Glioma / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Quinolinas / Inibidores de Proteínas Quinases / Glioma / Neoplasias / Antineoplásicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article