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Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells.
Dolatshad, H; Pellagatti, A; Fernandez-Mercado, M; Yip, B H; Malcovati, L; Attwood, M; Przychodzen, B; Sahgal, N; Kanapin, A A; Lockstone, H; Scifo, L; Vandenberghe, P; Papaemmanuil, E; Smith, C W J; Campbell, P J; Ogawa, S; Maciejewski, J P; Cazzola, M; Savage, K I; Boultwood, J.
Afiliação
  • Dolatshad H; LLR Molecular Haematology Unit, NDCLS, RDM, University of Oxford, Oxford, UK.
  • Pellagatti A; LLR Molecular Haematology Unit, NDCLS, RDM, University of Oxford, Oxford, UK.
  • Fernandez-Mercado M; LLR Molecular Haematology Unit, NDCLS, RDM, University of Oxford, Oxford, UK.
  • Yip BH; LLR Molecular Haematology Unit, NDCLS, RDM, University of Oxford, Oxford, UK.
  • Malcovati L; 1] Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy [2] Department of Molecular Medicine and Medical Therapy, University of Pavia, Pavia, Italy.
  • Attwood M; LLR Molecular Haematology Unit, NDCLS, RDM, University of Oxford, Oxford, UK.
  • Przychodzen B; Department of Translational Haematology and Oncology Research, Taussig Cancer Institute, Cleveland, OH, USA.
  • Sahgal N; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Kanapin AA; Department of Oncology, University of Oxford, Oxford, UK.
  • Lockstone H; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Scifo L; LLR Molecular Haematology Unit, NDCLS, RDM, University of Oxford, Oxford, UK.
  • Vandenberghe P; Center for Human Genetics, Katholieke Universiteit Leuven/University Hospital Leuven, Leuven, Belgium.
  • Papaemmanuil E; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Smith CW; Department of Biochemistry, Downing Site, University of Cambridge, Cambridge, UK.
  • Campbell PJ; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Ogawa S; Cancer Genomics Projects, Graduate School of Medicine, Tokyo, Japan.
  • Maciejewski JP; Department of Translational Haematology and Oncology Research, Taussig Cancer Institute, Cleveland, OH, USA.
  • Cazzola M; 1] Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy [2] Department of Molecular Medicine and Medical Therapy, University of Pavia, Pavia, Italy.
  • Savage KI; Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, UK.
  • Boultwood J; LLR Molecular Haematology Unit, NDCLS, RDM, University of Oxford, Oxford, UK.
Leukemia ; 29(5): 1092-103, 2015 May.
Article em En | MEDLINE | ID: mdl-25428262
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Células-Tronco / Síndromes Mielodisplásicas / Células-Tronco Hematopoéticas / Regulação Neoplásica da Expressão Gênica / Ribonucleoproteína Nuclear Pequena U2 Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Células-Tronco / Síndromes Mielodisplásicas / Células-Tronco Hematopoéticas / Regulação Neoplásica da Expressão Gênica / Ribonucleoproteína Nuclear Pequena U2 Idioma: En Ano de publicação: 2015 Tipo de documento: Article