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Dacomitinib compared with placebo in pretreated patients with advanced or metastatic non-small-cell lung cancer (NCIC CTG BR.26): a double-blind, randomised, phase 3 trial.
Ellis, Peter M; Shepherd, Frances A; Millward, Michael; Perrone, Francesco; Seymour, Lesley; Liu, Geoffrey; Sun, Sophie; Cho, Byoung Chul; Morabito, Alessandro; Leighl, Natasha B; Stockler, Martin R; Lee, Christopher W; Wierzbicki, Rafal; Cohen, Victor; Blais, Normand; Sangha, Randeep S; Favaretto, Adolfo G; Kang, Jin Hyoung; Tsao, Ming-Sound; Wilson, Carolyn F; Goldberg, Zelanna; Ding, Keyue; Goss, Glenwood D; Bradbury, Penelope Ann.
Afiliação
  • Ellis PM; Juravinski Cancer Centre, Hamilton, ON, Canada. Electronic address: Peter.Ellis@jcc.hhsc.ca.
  • Shepherd FA; Princess Margaret Cancer Centre, Toronto, ON, Canada.
  • Millward M; University of Western Australia, Perth, WA, Australia; Australasian Lung Cancer Trials Group, Sydney, NSW, Australia.
  • Perrone F; Clinical Trials Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori-Fondazione G Pascale IRCCS, Napoli, Italy.
  • Seymour L; NCIC Clinical Trials Group, Queen's University, ON, Canada.
  • Liu G; Princess Margaret Cancer Centre, Toronto, ON, Canada.
  • Sun S; British Columbia Cancer Agency, Vancouver Centre, Vancouver, BC, Canada.
  • Cho BC; Yonsei Cancer Centre, Yonsei University College of Medicine, Seoul, South Korea.
  • Morabito A; Thoraco-Pulmonary Medical Oncology, Istituto Nazionale Tumori "Fondazione G Pascale"-IRCCS, Napoli, Italy.
  • Leighl NB; Princess Margaret Cancer Centre, Toronto, ON, Canada.
  • Stockler MR; NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW, Australia.
  • Lee CW; British Columbia Cancer Agency, Fraser Valley Centre, Surrey, BC, Canada.
  • Wierzbicki R; R S MacLaughlin Durham RegionalCancer Centre, Oshawa, ON, Canada.
  • Cohen V; Jewish General Hospital and Segal Cancer Centre, McGill University, Montreal, QC, Canada.
  • Blais N; Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada.
  • Sangha RS; Cross Cancer Institute, Edmonton, AB, Canada.
  • Favaretto AG; Istituto Oncologico Veneto, Padua, Italy.
  • Kang JH; Seoul St Mary's Hospital, The Catholic University, Seoul, South Korea.
  • Tsao MS; Princess Margaret Cancer Centre, Toronto, ON, Canada.
  • Wilson CF; NCIC Clinical Trials Group, Queen's University, ON, Canada.
  • Goldberg Z; Pfizer Oncology, La Jolla, CA, USA.
  • Ding K; NCIC Clinical Trials Group, Queen's University, ON, Canada.
  • Goss GD; Division of Medical Oncology, University of Ottawa, Ottawa, ON, Canada.
  • Bradbury PA; NCIC Clinical Trials Group, Queen's University, ON, Canada.
Lancet Oncol ; 15(12): 1379-88, 2014 Nov.
Article em En | MEDLINE | ID: mdl-25439692
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Carcinoma Pulmonar de Células não Pequenas / Proteínas ras / Inibidores de Proteínas Quinases / Quinazolinonas Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Carcinoma Pulmonar de Células não Pequenas / Proteínas ras / Inibidores de Proteínas Quinases / Quinazolinonas Idioma: En Ano de publicação: 2014 Tipo de documento: Article