Selectivity of aggregation-determining interactions.

Ganesan, Ashok; Debulpaep, Maja; Wilkinson, Hannah; Van Durme, Joost; De Baets, Greet; Jonckheere, Wim; Ramakers, Meine; Ivarsson, Ylva; Zimmermann, Pascale; Van Eldere, Johan; Schymkowitz, Joost; Rousseau, Frederic

Ganesan, Ashok; Debulpaep, Maja; Wilkinson, Hannah; Van Durme, Joost; De Baets, Greet; Jonckheere, Wim; Ramakers, Meine; Ivarsson, Ylva; Zimmermann, Pascale; Van Eldere, Johan; Schymkowitz, Joost; Rousseau, Frederic.

Afiliação

Ganesan A; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, KU Leuven, B-3000 Leuven, Belgium.
Debulpaep M; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
Wilkinson H; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, KU Leuven, B-3000 Leuven, Belgium.
Van Durme J; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
De Baets G; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, KU Leuven, B-3000 Leuven, Belgium.
Jonckheere W; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
Ramakers M; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, KU Leuven, B-3000 Leuven, Belgium.
Ivarsson Y; Department of Human Genetics, KU Leuven, B-3000 Leuven, Belgium; Department of Chemistry-BMC, Uppsala University, Box 576, 751 23 Uppsala, Sweden.
Zimmermann P; Department of Human Genetics, KU Leuven, B-3000 Leuven, Belgium.
Van Eldere J; Department of Medical Diagnostic Sciences, KU Leuven, B-3000 Leuven, Belgium.
Schymkowitz J; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, KU Leuven, B-3000 Leuven, Belgium. Electronic address: joost.schymkowitz@switch-vib.kuleuven.be.
Rousseau F; VIB Switch Laboratory, VIB, B-3000 Leuven, Belgium; Department of Cellular and Molecular Medicine, KU Leuven, B-3000 Leuven, Belgium. Electronic address: Frederic.Rousseau@switch-vib.kuleuven.be.

J Mol Biol ; 427(2): 236-47, 2015 Jan 30.

Article em En | MEDLINE | ID: mdl-25451783

Assuntos

Proteínas de Bactérias/genética; Agregados Proteicos; Mapas de Interação de Proteínas; beta-Galactosidase/genética; Proteínas de Bactérias/metabolismo; Proteína C-Reativa/genética; Proteína C-Reativa/metabolismo; Escherichia coli/genética; Escherichia coli/metabolismo; Humanos; Masculino; Chaperonas Moleculares/genética; Chaperonas Moleculares/metabolismo; Peptídeos/metabolismo; Antígeno Prostático Específico/sangue; Antígeno Prostático Específico/genética; Ligação Proteica/genética; Proteoma/genética; Proteoma/metabolismo; Proteômica/métodos; Espectroscopia de Infravermelho com Transformada de Fourier; beta-Galactosidase/metabolismo

Palavras-chave

amyloid; detection; interaction; protein aggregation; specificity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Beta-Galactosidase / Mapas de Interação de Proteínas / Agregados Proteicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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