Analysis of the cis-acting requirements for germ-line-specific splicing of the P-element ORF2-ORF3 intron.
Genes Dev
; 3(5): 720-8, 1989 May.
Article
em En
| MEDLINE
| ID: mdl-2545526
ABSTRACT
P-element transposition is limited to the germ line because the element's third intron is only spliced in germ line cells. We show that a 240-bp fragment containing this 190-bp intron can confer germ line specificity when placed in the context of another gene. We find that the cis-acting regulatory sequences required for germ line regulation map near to, but not at, the 5' or 3' splice junctions.
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Base de dados:
MEDLINE
Assunto principal:
Elementos de DNA Transponíveis
/
Íntrons
/
Sequências Reguladoras de Ácido Nucleico
/
Splicing de RNA
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article