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Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.
Zheng, Christina L; Wang, Nicholas J; Chung, Jongsuk; Moslehi, Homayoun; Sanborn, J Zachary; Hur, Joseph S; Collisson, Eric A; Vemula, Swapna S; Naujokas, Agne; Chiotti, Kami E; Cheng, Jeffrey B; Fassihi, Hiva; Blumberg, Andrew J; Bailey, Celeste V; Fudem, Gary M; Mihm, Frederick G; Cunningham, Bari B; Neuhaus, Isaac M; Liao, Wilson; Oh, Dennis H; Cleaver, James E; LeBoit, Philip E; Costello, Joseph F; Lehmann, Alan R; Gray, Joe W; Spellman, Paul T; Arron, Sarah T; Huh, Nam; Purdom, Elizabeth; Cho, Raymond J.
Afiliação
  • Zheng CL; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Sciences University, Portland, OR 97239, USA; Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR 97239, USA.
  • Wang NJ; Department of Biomedical Engineering, Oregon Health & Sciences University, Portland, OR 97239, USA.
  • Chung J; Emerging Technology Research Center, Samsung Advanced Institute of Technology, Kyunggi-do 446-712, Korea.
  • Moslehi H; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Sanborn JZ; Five3 Genomics, LLC, Santa Cruz, CA 95060, USA.
  • Hur JS; Headquarters, Samsung Electronics, Seocho-gu, Seoul 137-857, Korea.
  • Collisson EA; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Vemula SS; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Naujokas A; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Chiotti KE; Department of Molecular and Medical Genetics, Oregon Health & Sciences University, Portland, OR 97239, USA.
  • Cheng JB; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Fassihi H; National Xeroderma Pigmentosum Service, St John's Institute of Dermatology, Guy's and St Thomas' NHS Trust, London SE1 9RT, UK.
  • Blumberg AJ; Department of Mathematics, University of Texas, Austin, Austin, TX 78712, USA.
  • Bailey CV; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94158, USA.
  • Fudem GM; Department of Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA.
  • Mihm FG; Department of Anesthesiology, Pain and Perioperative Medicine, Stanford University Medical Center, Stanford, CA 94305, USA.
  • Cunningham BB; Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA.
  • Neuhaus IM; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Liao W; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Oh DH; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA; Dermatology Research Unit, Veterans Affairs Medical Center, San Francisco, San Francisco, CA 94121, USA.
  • Cleaver JE; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • LeBoit PE; Department of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Costello JF; Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA.
  • Lehmann AR; Genome Damage and Stability Centre, University of Sussex, Brighton BN1 9RH, UK.
  • Gray JW; Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR 97239, USA; Department of Biomedical Engineering, Oregon Health & Sciences University, Portland, OR 97239, USA.
  • Spellman PT; Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR 97239, USA; Department of Molecular and Medical Genetics, Oregon Health & Sciences University, Portland, OR 97239, USA.
  • Arron ST; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Huh N; Emerging Technology Research Center, Samsung Advanced Institute of Technology, Kyunggi-do 446-712, Korea.
  • Purdom E; Department of Statistics, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: epurdom@stat.berkeley.edu.
  • Cho RJ; Department of Dermatology, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: chorj@derm.ucsf.edu.
Cell Rep ; 9(4): 1228-34, 2014 Nov 20.
Article em En | MEDLINE | ID: mdl-25456125
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Transcrição Gênica / Heterocromatina / Carcinoma de Células Escamosas / Genoma Humano / Reparo do DNA / Taxa de Mutação Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Transcrição Gênica / Heterocromatina / Carcinoma de Células Escamosas / Genoma Humano / Reparo do DNA / Taxa de Mutação Idioma: En Ano de publicação: 2014 Tipo de documento: Article