Luminal signaling: it's what's on the inside that counts.
Dev Cell
; 31(5): 519-20, 2014 Dec 08.
Article
em En
| MEDLINE
| ID: mdl-25490261
ABSTRACT
During organogenesis, FGFs are diffusible communication signals that allow cells to coordinate morphogenesis and establish tissue architecture. Recently in Nature, Durdu et al. (2014) show that epithelial cell clusters secrete FGFs into a microlumen, restricting FGF localization so that participating cells coordinate differentiation and collective migration via luminal signaling.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peixe-Zebra
/
Transdução de Sinais
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Comunicação Celular
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Organogênese
Idioma:
En
Ano de publicação:
2014
Tipo de documento:
Article