Effects of ROCK inhibitor Y27632 and EGFR inhibitor PD168393 on human neural precursors co-cultured with rat auditory brainstem explant.

Novozhilova, E; Englund-Johansson, U; Kale, A; Jiao, Y; Olivius, P

Novozhilova, E; Englund-Johansson, U; Kale, A; Jiao, Y; Olivius, P.

Afiliação

Novozhilova E; Center for Hearing and Communication Research and the Department of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institute, Karolinska University Hospital, Stockholm 17176, Sweden. Electronic address: 1035bms@gmail.com.
Englund-Johansson U; Department of Ophthalmology, Institution of Clinical Sciences in Lund, Lund University, 221 84 Lund, Sweden.
Kale A; Center for Hearing and Communication Research and the Department of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institute, Karolinska University Hospital, Stockholm 17176, Sweden.
Jiao Y; Center for Hearing and Communication Research and the Department of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institute, Karolinska University Hospital, Stockholm 17176, Sweden; Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical
Olivius P; Center for Hearing and Communication Research and the Department of Clinical Sciences, Intervention and Technology (CLINTEC), Karolinska Institute, Karolinska University Hospital, Stockholm 17176, Sweden; Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping Univers

Neuroscience ; 287: 43-54, 2015 Feb 26.

Article em En | MEDLINE | ID: mdl-25514049

Assuntos

Núcleo Coclear/citologia; Núcleo Coclear/metabolismo; Receptores ErbB/metabolismo; Células-Tronco Neurais/citologia; Células-Tronco Neurais/metabolismo; Transdução de Sinais; Quinases Associadas a rho/metabolismo; Amidas/farmacologia; Animais; Tronco Encefálico/citologia; Tronco Encefálico/metabolismo; Movimento Celular/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Técnicas de Cocultura; Inibidores Enzimáticos/farmacologia; Receptores ErbB/antagonistas & inibidores; Humanos; Neuroglia/citologia; Neuroglia/metabolismo; Piridinas/farmacologia; Quinazolinas/farmacologia; Ratos; Ratos Sprague-Dawley; Técnicas de Cultura de Tecidos; Quinases Associadas a rho/antagonistas & inibidores

Palavras-chave

PD168393; Y27632; hearing; neuronal restoration; organotypic culture

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Núcleo Coclear / Quinases Associadas a rho / Células-Tronco Neurais / Receptores ErbB Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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