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[Bronchial thermoplasty in the treatment of severe adult asthma]. / La thermoplastie bronchique dans le traitement de l'asthme sévère de l'adulte.
Chanez, P; Boulet, L-P; Brillet, P-Y; Joos, G; Laviolette, M; Louis, R; Rochat, T; Soccal, P; Aubier, M.
Afiliação
  • Chanez P; Inserm U1067 CNRS UMR 7333, service de pneumologie, AP-HM, Aix Marseille université, chemin des Bourrely, 13015 Marseille, France. Electronic address: pascal.chanez@univ-amu.fr.
  • Boulet LP; Centre de recherche, institut de cardiologie et de pneumologie de l'université Laval Québec, Québec, Canada.
  • Brillet PY; Département de radiologie, AP-HP Avicenne, 93000 Bobigny, France.
  • Joos G; Département de pneumologie, CHU de Gand, université de Gand, Gand, Belgique.
  • Laviolette M; Centre de recherche, institut de cardiologie et de pneumologie de l'université Laval Québec, Québec, Canada.
  • Louis R; Département de pneumologie, CHU de Liège, GIGAI3 groupe de recherche, université de Liège, Liège, Belgique.
  • Rochat T; Département de pneumologie, hôpitaux universitaires de Genève, Genève, Suisse.
  • Soccal P; Département de pneumologie, hôpitaux universitaires de Genève, Genève, Suisse.
  • Aubier M; U700 Inserm DHU, service de pneumologie, AP-HP Bichat, université Diderot Paris, 75018 Paris, France.
Rev Mal Respir ; 32(2): 97-109, 2015 Feb.
Article em Fr | MEDLINE | ID: mdl-25534552
Bronchial thermoplasty is a recent endoscopic technique for the treatment of severe asthma. It is an innovative treatment whose clinical efficacy and safety are beginning to be better understood. Since this is a device-based treatment, the evaluation procedure of risks and benefits is different that for pharmaceutical products; safety aspects, regulatory requirements, study design and the assessment of the magnitude of effects may all be different. The mechanism of action and optimal patient selection need to be assessed further in rigorous clinical and scientific studies. This technique is in harmony with the development of personalised medicine in the 21st century. It should be developed further in response to the numerous challenges and needs not yet met in the management of severe asthma.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Brônquios / Broncoscopia / Eletrocoagulação Idioma: Fr Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Brônquios / Broncoscopia / Eletrocoagulação Idioma: Fr Ano de publicação: 2015 Tipo de documento: Article