Construction of the tricyclic core of steenkrotin-type diterpenoids via intramolecular [3 + 2] cycloaddition.
Org Biomol Chem
; 13(6): 1643-6, 2015 Feb 14.
Article
em En
| MEDLINE
| ID: mdl-25535835
ABSTRACT
A concise and diastereoselective route to the angularly fused [5-6-7] tricyclic carbon framework of the steenkrotin-type diterpenoids was reported. The key features of the strategy are based on an intramolecular nitrile oxide/alkene [3 + 2] cycloaddition and a regio-selective aldol/dehydration sequence.
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1
Base de dados:
MEDLINE
Assunto principal:
Diterpenos
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article