Inhibition of placental growth factor in renal cell carcinoma.

Bessho, Hideharu; Wong, Bernice; Huang, Dan; Siew, Ee Yan; Huang, Dachuan; Tan, Jing; Ong, Choon Kiat; Tan, Soo Yong; Matsumoto, Kazumasa; Iwamura, Masatsugu; Teh, Bin Tean

Bessho, Hideharu; Wong, Bernice; Huang, Dan; Siew, Ee Yan; Huang, Dachuan; Tan, Jing; Ong, Choon Kiat; Tan, Soo Yong; Matsumoto, Kazumasa; Iwamura, Masatsugu; Teh, Bin Tean.

Afiliação

Bessho H; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore Department of Urology, Kitasato University School of Medicine, Kanagawa, Japan hideji56@gmail.com.
Wong B; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore.
Huang D; Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, MI, U.S.A.
Siew EY; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore.
Huang D; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore.
Tan J; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore.
Ong CK; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore.
Tan SY; Department of Pathology, Singapore General Hospital, Singapore, Singapore.
Matsumoto K; Department of Urology, Kitasato University School of Medicine, Kanagawa, Japan.
Iwamura M; Department of Urology, Kitasato University School of Medicine, Kanagawa, Japan.
Teh BT; Laboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore, Singapore Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore, Singapore Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.

Anticancer Res ; 35(1): 531-41, 2015 Jan.

Article em En | MEDLINE | ID: mdl-25550599

Assuntos

Anticorpos Monoclonais/uso terapêutico; Antineoplásicos/uso terapêutico; Carcinoma de Células Renais/tratamento farmacológico; Neoplasias Renais/tratamento farmacológico; Proteínas da Gravidez/antagonistas & inibidores; Animais; Anticorpos Monoclonais/farmacologia; Anticorpos Monoclonais Humanizados; Antineoplásicos/farmacologia; Carcinoma de Células Renais/irrigação sanguínea; Carcinoma de Células Renais/metabolismo; Carcinoma de Células Renais/patologia; Linhagem Celular Tumoral; Resistencia a Medicamentos Antineoplásicos; Feminino; Humanos; Indóis/farmacologia; Neoplasias Renais/irrigação sanguínea; Neoplasias Renais/metabolismo; Neoplasias Renais/patologia; Camundongos Nus; Neovascularização Patológica/tratamento farmacológico; Fator de Crescimento Placentário; Proteínas da Gravidez/sangue; Pirróis/farmacologia; Sunitinibe; Transcriptoma/efeitos dos fármacos; Carga Tumoral/efeitos dos fármacos; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

Placental growth factor (PlGF); antiangiogenic therapy; renal cell carcinoma; sunitinib resistance

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Base de dados: MEDLINE Assunto principal: Proteínas da Gravidez / Carcinoma de Células Renais / Neoplasias Renais / Anticorpos Monoclonais / Antineoplásicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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