Quantitative comparison of macular segmentation performance using identical retinal regions across multiple spectral-domain optical coherence tomography instruments.
Br J Ophthalmol
; 99(6): 794-800, 2015 Jun.
Article
em En
| MEDLINE
| ID: mdl-25563763
ABSTRACT
PURPOSE:
Comparison of optical coherence tomography (OCT) segmentation performance regarding technical accuracy and clinical relevance.METHODS:
29 eyes were imaged prospectively with Spectralis (Sp), Cirrus (Ci), 3D-OCT 2000 (3D) and RS-3000 (RS) OCTs. Raw data were evaluated in validated custom software. A 1â mm diameter subfield, centred on the fovea, was investigated to compare identical regions for each case. Segmentation errors were corrected on each B-scan enclosed in this subfield. Proportions of wrongly segmented A-scans were noted for inner and outer retinal boundaries. Centre point thickness (CPT) and central macular thickness (CMT) were compared before and after correction.RESULTS:
Segmentation errors occurred in 77% and affected on average 29% of A-scans, resulting in mean differences of 24/13â µm (CPT/CMT). The incidence of segmentation errors was 48% (Sp), 79% (Ci), 86% (3D) and 93% (RS), p<0.001. Mean proportions of A-scans with wrong outer retinal boundary were 30% (Sp), 9% (Ci), 23% (3D) and 10% (RS), p=0.006; proportions for the inner retinal boundary were 11% (Sp), 12% (Ci), 6% (3D) and 21% (RS), p=0.034. Mean deviations in CPT/CMT were 41/28â µm (Sp), 17/11â µm (Ci), 30/13â µm (3D) and 18/8â µm (RS), p=0.409/0.477.CONCLUSIONS:
By comparison of identical regions, substantial differences were detected between the tested OCT devices regarding technical accuracy and clinical impact. Spectralis showed lowest error incidence but highest error impact.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Retina
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Doenças Retinianas
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Algoritmos
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Artefatos
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Tomografia de Coerência Óptica
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Erros de Diagnóstico
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article