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Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution.
Head, Stewart I; Chan, Stephen; Houweling, Peter J; Quinlan, Kate G R; Murphy, Robyn; Wagner, Sören; Friedrich, Oliver; North, Kathryn N.
Afiliação
  • Head SI; School of Medical Sciences, University of New South Wales, Sydney, Australia.
  • Chan S; School of Medical Sciences, University of New South Wales, Sydney, Australia.
  • Houweling PJ; Murdoch Children's Research Institute, Melbourne, Australia; Institute for Neuroscience and Muscle Research, The Children's Hospital Westmead, Sydney, Australia.
  • Quinlan KG; Institute for Neuroscience and Muscle Research, The Children's Hospital Westmead, Sydney, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, The University of Sydney, Sydney, Australia.
  • Murphy R; Department of Zoology, La Trobe University, Melbourne, Australia.
  • Wagner S; Department of Anaesthesiology, University Clinic Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
  • Friedrich O; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
  • North KN; Murdoch Children's Research Institute, Melbourne, Australia; Institute for Neuroscience and Muscle Research, The Children's Hospital Westmead, Sydney, Australia; Institute of Medical Biotechnology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
PLoS Genet ; 11(2): e1004862, 2015.
Article em En | MEDLINE | ID: mdl-25590636
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Seleção Genética / Actinina / Cálcio / Evolução Biológica / Doenças Musculares Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Seleção Genética / Actinina / Cálcio / Evolução Biológica / Doenças Musculares Idioma: En Ano de publicação: 2015 Tipo de documento: Article