Occupational exposures and risk of stomach and esophageal cancers: update of a cohort of female textile workers in Shanghai, China.
Am J Ind Med
; 58(3): 267-75, 2015 Mar.
Article
em En
| MEDLINE
| ID: mdl-25611949
ABSTRACT
BACKGROUND:
Associations between stomach and esophageal cancer and exposures to dusts, metals, chemicals, and endotoxin in the workplace are not very well understood, particularly in women.METHODS:
We followed 267,400 female textile workers in Shanghai, China for cancer incidence from 1989 to 2006. Stomach (n = 1374) and esophageal (n = 190) cancer cases were identified and a comparison subcohort (n = 3187) was randomly selected. Cox proportional hazard modeling was used, adjusting for age and smoking.RESULTS:
Increasing stomach cancer risk was observed with increasing duration of synthetic fiber dust exposure (p = 0.03), although the magnitude of effect was small (20 + years HR = 1.2, 95% CI 1.1-1.4). Trends with endotoxin exposure were modestly inversed for esophageal cancer and increased for stomach cancer, but with little deviation from a null association.CONCLUSIONS:
Our findings demonstrate that long durations of synthetic fiber dust exposure can increase stomach cancer risk in women, but provide limited support for associations with other textile industry exposures.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
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Indústria Têxtil
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Neoplasias Esofágicas
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Exposição Ocupacional
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Doenças Profissionais
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article