EGCG inhibits proliferation, invasiveness and tumor growth by up-regulation of adhesion molecules, suppression of gelatinases activity, and induction of apoptosis in nasopharyngeal carcinoma cells.

Fang, Chih-Yeu; Wu, Chung-Chun; Hsu, Hui-Yu; Chuang, Hsin-Ying; Huang, Sheng-Yen; Tsai, Ching-Hwa; Chang, Yao; Tsao, George Sai-Wah; Chen, Chi-Long; Chen, Jen-Yang

Fang, Chih-Yeu; Wu, Chung-Chun; Hsu, Hui-Yu; Chuang, Hsin-Ying; Huang, Sheng-Yen; Tsai, Ching-Hwa; Chang, Yao; Tsao, George Sai-Wah; Chen, Chi-Long; Chen, Jen-Yang.

Afiliação

Fang CY; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan. phildts@gmail.com.
Wu CC; National Institute of Cancer Research, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan. chungcwu@nhri.org.tw.
Hsu HY; National Institute of Cancer Research, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan. kakacoco0218@gmail.com.
Chuang HY; National Institute of Cancer Research, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan. tw.hitomi@gmail.com.
Huang SY; National Institute of Cancer Research, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan. syhuang@nhri.org.tw.
Tsai CH; Department of Microbiology, College of Medicine, National Taiwan University, Taipei 100, Taiwan. chtsai@ntu.edu.tw.
Chang Y; National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Tainan 701, Taiwan. yaochang@nhri.org.tw.
Tsao GS; Department of Anatomy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China. gswtsao@hkucc.hku.hk.
Chen CL; Department of Pathology, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan. chencl@tmu.edu.tw.
Chen JY; National Institute of Cancer Research, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan. cjy@nhri.org.tw.

Int J Mol Sci ; 16(2): 2530-58, 2015 Jan 23.

Article em En | MEDLINE | ID: mdl-25625511

Assuntos

Apoptose/efeitos dos fármacos; Catequina/análogos & derivados; Moléculas de Adesão Celular/metabolismo; Proliferação de Células/efeitos dos fármacos; Gelatinases/metabolismo; Animais; Caderinas/metabolismo; Carcinoma; Caspase 3/metabolismo; Catequina/farmacologia; Catequina/uso terapêutico; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Regulação para Baixo/efeitos dos fármacos; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Humanos; Camundongos; Camundongos SCID; NF-kappa B/metabolismo; Carcinoma Nasofaríngeo; Neoplasias Nasofaríngeas/tratamento farmacológico; Neoplasias Nasofaríngeas/enzimologia; Neoplasias Nasofaríngeas/metabolismo; Neoplasias Nasofaríngeas/patologia; Transdução de Sinais/efeitos dos fármacos; Esferoides Celulares/efeitos dos fármacos; Transplante Heterólogo; Regulação para Cima/efeitos dos fármacos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Catequina / Moléculas de Adesão Celular / Apoptose / Gelatinases / Proliferação de Células Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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