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Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.
Liu, Pengda; Gan, Wenjian; Guo, Chunguang; Xie, Anyong; Gao, Daming; Guo, Jianping; Zhang, Jinfang; Willis, Nicholas; Su, Arthur; Asara, John M; Scully, Ralph; Wei, Wenyi.
Afiliação
  • Liu P; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Gan W; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Guo C; Howeard Hughes Medical Institute, the Children's Hospital, the Immune Disease Institute and Harvard Medical School, Boston, MA 02115, USA.
  • Xie A; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA; Sir Run Run Shaw Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China.
  • Gao D; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Guo J; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Zhang J; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Willis N; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Su A; Howeard Hughes Medical Institute, the Children's Hospital, the Immune Disease Institute and Harvard Medical School, Boston, MA 02115, USA.
  • Asara JM; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Scully R; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.
  • Wei W; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address: wwei2@bidmc.harvard.edu.
Mol Cell ; 57(4): 648-661, 2015 Feb 19.
Article em En | MEDLINE | ID: mdl-25661488

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Enzimas Reparadoras do DNA / Proteínas de Ligação a DNA / Proteínas Proto-Oncogênicas c-akt / Reparo do DNA por Junção de Extremidades Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Enzimas Reparadoras do DNA / Proteínas de Ligação a DNA / Proteínas Proto-Oncogênicas c-akt / Reparo do DNA por Junção de Extremidades Idioma: En Ano de publicação: 2015 Tipo de documento: Article