Lentivirus-mediated inhibition of tumour necrosis factor-&#945; improves motor function associated with PRDX6 in spinal cord contusion rats.

Zhang, Xiao; Shi, Lan-lan; Gao, Xia; Jiang, Di; Zhong, Zhan-qiong; Zeng, Xi; Rao, Ying; Hu, Xi; Li, Tian-zhi; Li, Xiu-juan; Li, Lei; Chen, Jian-min; Xia, Qingjie; Wang, Ting-hua

Lentivirus-mediated inhibition of tumour necrosis factor-α improves motor function associated with PRDX6 in spinal cord contusion rats.

Zhang, Xiao; Shi, Lan-lan; Gao, Xia; Jiang, Di; Zhong, Zhan-qiong; Zeng, Xi; Rao, Ying; Hu, Xi; Li, Tian-zhi; Li, Xiu-juan; Li, Lei; Chen, Jian-min; Xia, Qingjie; Wang, Ting-hua.

Afiliação

Zhang X; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Shi LL; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Gao X; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Jiang D; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Zhong ZQ; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Zeng X; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Rao Y; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Hu X; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Li TZ; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Li XJ; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Li L; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Chen JM; Center for Experimental Technology of Preclinical Medicine, Chengdu Medical College, Chengdu 610083, Sichuan, China.
Xia Q; Institute of Neurological Diseases, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Wang TH; 1] Institute of Neuronscience, Kunming Medical University, Kunming 650031, China [2] Institute of Neurological Diseases, Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu 610041, China.

Sci Rep ; 5: 8486, 2015 Feb 16.

Article em En | MEDLINE | ID: mdl-25686213

Assuntos

Atividade Motora/genética; Peroxirredoxina VI/genética; Interferência de RNA; Traumatismos da Medula Espinal/genética; Traumatismos da Medula Espinal/fisiopatologia; Fator de Necrose Tumoral alfa/genética; Animais; Barreira Hematoencefálica/metabolismo; Modelos Animais de Doenças; Feminino; Expressão Gênica; Vetores Genéticos/administração & dosagem; Vetores Genéticos/genética; Lentivirus/genética; Peroxirredoxina VI/metabolismo; Transporte Proteico; Ratos; Traumatismos da Medula Espinal/metabolismo; Transdução Genética; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal / Fator de Necrose Tumoral alfa / Interferência de RNA / Peroxirredoxina VI / Atividade Motora Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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