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Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology.
Devalla, Harsha D; Schwach, Verena; Ford, John W; Milnes, James T; El-Haou, Said; Jackson, Claire; Gkatzis, Konstantinos; Elliott, David A; Chuva de Sousa Lopes, Susana M; Mummery, Christine L; Verkerk, Arie O; Passier, Robert.
Afiliação
  • Devalla HD; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands h.d.devalla@lumc.nl r.passier@lumc.nl.
  • Schwach V; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.
  • Ford JW; Xention Ltd, Cambridge, UK.
  • Milnes JT; Xention Ltd, Cambridge, UK.
  • El-Haou S; Xention Ltd, Cambridge, UK.
  • Jackson C; Xention Ltd, Cambridge, UK.
  • Gkatzis K; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.
  • Elliott DA; Murdoch Childrens Research Institute Royal Children's Hospital, Melbourne, Vic., Australia.
  • Chuva de Sousa Lopes SM; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands Department for Reproductive Medicine, Ghent University Hospital, Ghent, Belgium.
  • Mummery CL; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands.
  • Verkerk AO; Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Passier R; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, The Netherlands h.d.devalla@lumc.nl r.passier@lumc.nl.
EMBO Mol Med ; 7(4): 394-410, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25700171
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / Sistemas de Liberação de Medicamentos / Bloqueadores dos Canais de Potássio / Miócitos Cardíacos / Células-Tronco Pluripotentes / Modelos Biológicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / Sistemas de Liberação de Medicamentos / Bloqueadores dos Canais de Potássio / Miócitos Cardíacos / Células-Tronco Pluripotentes / Modelos Biológicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article