RP-HPLC analysis and in vitro identification of antimycobacterial activity of novel thiosemicarbazides and 1,2,4-triazole derivatives.

Flieger, Jolanta; Tatarczak-Michalewska, Malgorzata; Wujec, Monika; Pitucha, Monika; Swieboda, Ryszard

Flieger, Jolanta; Tatarczak-Michalewska, Malgorzata; Wujec, Monika; Pitucha, Monika; Swieboda, Ryszard.

Afiliação

Flieger J; Department of Analytical Chemistry, Medical University, Chodzki 4a, 20-093 Lublin, Poland. Electronic address: j.flieger@umlub.pl.
Tatarczak-Michalewska M; Department of Analytical Chemistry, Medical University, Chodzki 4a, 20-093 Lublin, Poland.
Wujec M; Department of Organic Chemistry, Medical University, Chodzki 4a, 20-093 Lublin, Poland.
Pitucha M; Department of Organic Chemistry, Medical University, Chodzki 4a, 20-093 Lublin, Poland.
Swieboda R; Department of Inorganic Chemistry, Medical University of Lublin, Chodzki 1, 20-093 Lublin, Poland.

J Pharm Biomed Anal ; 107: 501-11, 2015 Mar 25.

Article em En | MEDLINE | ID: mdl-25700183

Assuntos

Antibacterianos/química; Antibacterianos/farmacologia; Mycobacterium tuberculosis/efeitos dos fármacos; Semicarbazidas/química; Semicarbazidas/farmacologia; Triazóis/química; Triazóis/farmacologia; Cromatografia Líquida de Alta Pressão/métodos; Testes de Sensibilidade Microbiana/métodos; Análise de Componente Principal; Relação Quantitativa Estrutura-Atividade

Palavras-chave

1,2,4-Triazole derivatives; Antimycobacterial activity; Experimental lipophilicity; RP-HPLC; Thiosemicarbazides

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Semicarbazidas / Triazóis / Antibacterianos / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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