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Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association.
Martin, Anthony; Xiong, Jian; Koromila, Theodora; Ji, Jie S; Chang, Stephanie; Song, Yae S; Miller, Jonathan L; Han, Chun-Ya; Kostenuik, Paul; Krum, Susan A; Chimge, Nyam-Osor; Gabet, Yankel; Frenkel, Baruch.
Afiliação
  • Martin A; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA. Electronic
  • Xiong J; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA. Electronic
  • Koromila T; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA. Electronic
  • Ji JS; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA.
  • Chang S; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA. Electronic address: schan061@ucr.edu.
  • Song YS; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA. Electronic address: yaesamso@usc.edu.
  • Miller JL; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA. Electronic address: mill252@usc.edu.
  • Han CY; Metabolic Disorders Research, Amgen Inc., 1 Amgen Center Dr, Thousand Oaks, CA 91320, USA. Electronic address: ehan@amgen.com.
  • Kostenuik P; Metabolic Disorders Research, Amgen Inc., 1 Amgen Center Dr, Thousand Oaks, CA 91320, USA. Electronic address: paulk@amgen.com.
  • Krum SA; UCLA and Orthopaedic Hospital Department of Orthopaedic Surgery and the Orthopaedic Hospital Research Center, David Geffen School of Medicine, UCLA, 10833 Le Conte Ave, Los Angeles, CA 90095, USA. Electronic address: smirand5@uthsc.edu.
  • Chimge NO; Department of Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA; Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA. Electronic address: chimgee@usc.edu.
  • Gabet Y; Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel. Electronic address: yagabet@gmail.com.
  • Frenkel B; Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA; Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, 1795 Zonal Ave, Los Angeles, CA 90033, USA; Institu
Bone ; 75: 96-104, 2015 Jun.
Article em En | MEDLINE | ID: mdl-25701138

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoblastos / Osteoclastos / Reabsorção Óssea / Estrogênios / Subunidade alfa 1 de Fator de Ligação ao Core / Ligante RANK Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoblastos / Osteoclastos / Reabsorção Óssea / Estrogênios / Subunidade alfa 1 de Fator de Ligação ao Core / Ligante RANK Idioma: En Ano de publicação: 2015 Tipo de documento: Article