Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay.

Opota, O; Desgraz, B; Kenfak, A; Jaton, K; Cavassini, M; Greub, G; Prod'hom, G; Giulieri, S

Opota, O; Desgraz, B; Kenfak, A; Jaton, K; Cavassini, M; Greub, G; Prod'hom, G; Giulieri, S.

Afiliação

Opota O; Institute of Microbiology, Switzerland.
Desgraz B; Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
Kenfak A; Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
Jaton K; Institute of Microbiology, Switzerland.
Cavassini M; Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
Greub G; Institute of Microbiology, Switzerland ; Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
Prod'hom G; Institute of Microbiology, Switzerland.
Giulieri S; Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.

New Microbes New Infect ; 4: 1-4, 2015 Mar.

Article em En | MEDLINE | ID: mdl-25755893

RESUMO

Detection of cryptococcal antigen in serum or cerebrospinal fluid allows cryptococcal meningitis diagnosis within few hours with >90% sensitivity. In an HIV-positive patient with Cryptococcus neoformans meningitis, initial antigen detection by immunoagglutination was negative. We thus evaluated a new immunochromatographic detection assay that exhibited a higher sensitivity.

Palavras-chave

Antigen test; Cryptococcus neoformans; HIV; immunochromatography; meningitis

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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