TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice.

Vlantis, Katerina; Polykratis, Apostolos; Welz, Patrick-Simon; van Loo, Geert; Pasparakis, Manolis; Wullaert, Andy

Vlantis, Katerina; Polykratis, Apostolos; Welz, Patrick-Simon; van Loo, Geert; Pasparakis, Manolis; Wullaert, Andy.

Afiliação

Vlantis K; Institute for Genetics, University of Cologne, Cologne, Germany Centre for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Polykratis A; Institute for Genetics, University of Cologne, Cologne, Germany Centre for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Welz PS; Institute for Genetics, University of Cologne, Cologne, Germany Centre for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany Institute for Research i
van Loo G; Inflammation Research Center, VIB, Ghent, Belgium Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
Pasparakis M; Institute for Genetics, University of Cologne, Cologne, Germany Centre for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Wullaert A; Institute for Genetics, University of Cologne, Cologne, Germany Centre for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany Department of Medical Pr

Gut ; 65(6): 935-43, 2016 06.

Article em En | MEDLINE | ID: mdl-25761602

Assuntos

Colite/genética; Colite/prevenção & controle; Fator 6 Associado a Receptor de TNF/genética; Receptores Toll-Like/genética; Animais; Colite/etiologia; Colite/patologia; Colo/metabolismo; Sulfato de Dextrana/farmacologia; Modelos Animais de Doenças; Marcadores Genéticos/genética; Mucosa Intestinal/metabolismo; Camundongos; Microbiota/genética; Transdução de Sinais/genética

Palavras-chave

EXPERIMENTAL COLITIS; GUT INFLAMMATION

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colite / Fator 6 Associado a Receptor de TNF / Receptores Toll-Like Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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