MiR-26a modulates extracellular matrix homeostasis in cartilage.

Etich, Julia; Holzer, Tatjana; Pitzler, Lena; Bluhm, Björn; Brachvogel, Bent

Etich, Julia; Holzer, Tatjana; Pitzler, Lena; Bluhm, Björn; Brachvogel, Bent.

Afiliação

Etich J; Experimental Neonatology, Department of Pediatrics and Adolescent Medicine, Medical Faculty, University of Cologne, Cologne, Germany; Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
Holzer T; Experimental Neonatology, Department of Pediatrics and Adolescent Medicine, Medical Faculty, University of Cologne, Cologne, Germany; Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
Pitzler L; Experimental Neonatology, Department of Pediatrics and Adolescent Medicine, Medical Faculty, University of Cologne, Cologne, Germany; Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
Bluhm B; Experimental Neonatology, Department of Pediatrics and Adolescent Medicine, Medical Faculty, University of Cologne, Cologne, Germany; Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany.
Brachvogel B; Experimental Neonatology, Department of Pediatrics and Adolescent Medicine, Medical Faculty, University of Cologne, Cologne, Germany; Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany. Electronic address: bent.brachvogel@uni-koeln.de.

Matrix Biol ; 43: 27-34, 2015 Apr.

Article em En | MEDLINE | ID: mdl-25766405

Assuntos

Doenças das Cartilagens/genética; Condrócitos/metabolismo; Matriz Extracelular/metabolismo; MicroRNAs/genética; MicroRNAs/metabolismo; Regiões 3' não Traduzidas; Animais; Antígenos CD/genética; Antígenos CD/metabolismo; Doenças das Cartilagens/patologia; Células Cultivadas; Condrócitos/patologia; Colágeno Tipo IX/genética; Colágeno Tipo IX/metabolismo; Colágeno Tipo X/genética; Colágeno Tipo X/metabolismo; Biologia Computacional/métodos; Fator de Crescimento do Tecido Conjuntivo/genética; Fator de Crescimento do Tecido Conjuntivo/metabolismo; Matriz Extracelular/genética; Hipertrofia/genética; Camundongos

Palavras-chave

CD200; Cartilage; Collagen; Extracellular matrix; Growth plate; MiR-26a

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças das Cartilagens / Condrócitos / MicroRNAs / Matriz Extracelular Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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