Structural and Functional Diversity of Peptide Toxins from Tarantula Haplopelma hainanum (Ornithoctonus hainana) Venom Revealed by Transcriptomic, Peptidomic, and Patch Clamp Approaches.

Zhang, Yi-Ya; Huang, Yong; He, Quan-Ze; Luo, Ji; Zhu, Li; Lu, Shan-Shan; Liu, Jin-Yan; Huang, Peng-Fei; Zeng, Xiong-Zhi; Liang, Song-Ping

Zhang, Yi-Ya; Huang, Yong; He, Quan-Ze; Luo, Ji; Zhu, Li; Lu, Shan-Shan; Liu, Jin-Yan; Huang, Peng-Fei; Zeng, Xiong-Zhi; Liang, Song-Ping.

Afiliação

Zhang YY; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and.
Huang Y; the State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dong-Da Street, Fengtai District, Beijing 100071, China.
He QZ; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and.
Luo J; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and.
Zhu L; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and.
Lu SS; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and.
Liu JY; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and.
Huang PF; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and.
Zeng XZ; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and xiongzhizeng@gmail.com.
Liang SP; From the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life Sciences, Hunan Normal University, Changsha 410081, China and liangsp@hunnu.edu.cn.

J Biol Chem ; 290(22): 14192-207, 2015 May 29.

Article em En | MEDLINE | ID: mdl-25770214

Assuntos

Proteômica/métodos; Venenos de Aranha/química; Sequência de Aminoácidos; Animais; Sequência de Bases; Cisteína/química; DNA Complementar/metabolismo; Etiquetas de Sequências Expressas; Deleção de Genes; Dados de Sequência Molecular; Mutação; Neurônios/metabolismo; Neurotoxinas/química; Técnicas de Patch-Clamp; Peptídeos/química; Filogenia; Processamento de Proteína Pós-Traducional; Ratos; Análise de Sequência de DNA; Homologia de Sequência de Aminoácidos; Homologia de Sequência do Ácido Nucleico; Aranhas; Transcrição Gênica

Palavras-chave

454 sequencing; Haplopelma hainanum; cysteine pattern; ion channel; molecular diversity; molecular evolution; neurotoxin; spider venom; toxin; transcription

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Venenos de Aranha / Proteômica Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Venenos de Aranha / Proteômica Idioma: En Ano de publicação: 2015 Tipo de documento: Article