Improved in vitro human tumor models for cancer gene therapy.
Hum Gene Ther
; 26(5): 249-56, 2015 May.
Article
em En
| MEDLINE
| ID: mdl-25808057
ABSTRACT
Developing effective anticancer treatments is a particular challenge, as agents must contend with not only the target cellular biology, but also with the complex tumor microenvironment. Here we discuss various in vitro strategies that have sought to address this issue, with a particular focus on new methodologies that utilize clinical samples in basic research and their application in gene therapy and virotherapy.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Terapia Genética
/
Neoplasias
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article