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Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.
Pawlikowski, Jeffrey S; Brock, Claire; Chen, Sheau-Chiann; Al-Olabi, Lara; Nixon, Colin; McGregor, Fiona; Paine, Simon; Chanudet, Estelle; Lambie, Wendy; Holmes, William M; Mullin, James M; Richmond, Ann; Wu, Hong; Blyth, Karen; King, Ayala; Kinsler, Veronica A; Adams, Peter D.
Afiliação
  • Pawlikowski JS; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK; Beatson Institute for Cancer Research, Glasgow, UK; Current address: Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Brock C; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK; Beatson Institute for Cancer Research, Glasgow, UK.
  • Chen SC; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Al-Olabi L; Genetics and Genomic Medicine, UCL Institute of Child Health, London, UK.
  • Nixon C; Beatson Institute for Cancer Research, Glasgow, UK.
  • McGregor F; Beatson Institute for Cancer Research, Glasgow, UK.
  • Paine S; Genetics and Genomic Medicine, UCL Institute of Child Health, London, UK.
  • Chanudet E; GOSgene, UCL Institute of Child Health, London, UK.
  • Lambie W; Beatson Institute for Cancer Research, Glasgow, UK.
  • Holmes WM; Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.
  • Mullin JM; Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.
  • Richmond A; Department of Veterans Affairs, Vanderbilt University Medical Center, Tennessee Valley Healthcare System, Nashville, Tennessee, USA; Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Wu H; Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA.
  • Blyth K; Beatson Institute for Cancer Research, Glasgow, UK.
  • King A; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Kinsler VA; Genetics and Genomic Medicine, UCL Institute of Child Health, London, UK; Pediatric Dermatology, Great Ormond St Hospital, London, UK. Electronic address: v.kinsler@ucl.ac.uk.
  • Adams PD; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK; Beatson Institute for Cancer Research, Glasgow, UK. Electronic address: p.adams@beatson.gla.ac.uk.
J Invest Dermatol ; 135(8): 2093-2101, 2015 Aug.
Article em En | MEDLINE | ID: mdl-25815427
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Transdução de Sinais / MAP Quinase Quinase Quinases / Proteínas Wnt / Proteínas de Membrana / Nevo Pigmentado Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Transdução de Sinais / MAP Quinase Quinase Quinases / Proteínas Wnt / Proteínas de Membrana / Nevo Pigmentado Idioma: En Ano de publicação: 2015 Tipo de documento: Article