Production of α2,6-sialylated IgG1 in CHO cells.
MAbs
; 7(3): 571-83, 2015.
Article
em En
| MEDLINE
| ID: mdl-25875452
Palavras-chave
B4GALT1; CHO cells; ECL, Erythrina Cristagalli lectin; GT, ß1,4-galactosyltransferase 1; HILIC, hydrophilic interaction liquid chromatography; IgG1; LC-ESI-MS, liquid chromatography coupled to electrospray ionization mass spectrometry; MAL-II, Maackia Amurensis lectin II; N-glycosylation; PEI, polyethylenimine; SIAT1; SNA, Sambucus Nigra agglutinin; ST6, α2,6-sialyltransferase 1; TZM, trastuzumab (Herceptin®); cIEF, capillary zone electrophoresis isoelectric focusing; mAbs, monoclonal antibodies; sialylation; transfection; α2,3SA, α2,3-linked sialic acid; α2,6SA, α2,6-linked sialic acid
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácidos Siálicos
/
Imunoglobulina G
/
Mutação de Sentido Incorreto
/
Anticorpos Monoclonais
Idioma:
En
Ano de publicação:
2015
Tipo de documento:
Article