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The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.
Giotopoulos, G; Chan, W-I; Horton, S J; Ruau, D; Gallipoli, P; Fowler, A; Crawley, C; Papaemmanuil, E; Campbell, P J; Göttgens, B; Van Deursen, J M; Cole, P A; Huntly, B J P.
Afiliação
  • Giotopoulos G; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
  • Chan WI; Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.
  • Horton SJ; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
  • Ruau D; Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.
  • Gallipoli P; State Key laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macau.
  • Fowler A; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
  • Crawley C; Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.
  • Papaemmanuil E; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
  • Campbell PJ; Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.
  • Göttgens B; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
  • Van Deursen JM; Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.
  • Cole PA; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
  • Huntly BJ; Department of Haematology, Cambridge Institute for Medical Research and Addenbrookes Hospital, University of Cambridge, Cambridge, UK.
Oncogene ; 35(3): 279-89, 2016 Jan 21.
Article em En | MEDLINE | ID: mdl-25893291
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Sialoglicoproteínas / Leucemia Mieloide Aguda / Epigênese Genética / Proteína p300 Associada a E1A Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Sialoglicoproteínas / Leucemia Mieloide Aguda / Epigênese Genética / Proteína p300 Associada a E1A Idioma: En Ano de publicação: 2016 Tipo de documento: Article